A manual sample preparation workflow for the analysis of drug-content in Levothyroxine Sodium Tablets (0.025 mg) was automated and the extraction times were optimized using the accroma® samplePrep system.

The goal was to reduce extraction- and overall sample preparation hands-on time without compromising recovery.

The overall handson time could be reduced from 30 min (manually) to 5 min with the accroma® without counting documentation time.

  • Hands-on time reduction 83% 83%
  • Extraction time reduction 90% 90%

Extraction times by the accroma® samplePrep system were shown to be significantly shorter than by the manual method of ultrasonication.

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